A Phase II Dose-Escalation Study to Assess the Feasibility and Safety of Transendocardial Delivery of Three Different Doses of Allogeneic Mesenchymal Progenitor Cells (MPCs) in Subjects With Heart Failure (SAFE HF)
The purpose of this study is to evaluate the feasibility and safety of transendocardial injection using mapping Catheter with the Left Ventricular Injection Catheter of 25 M, 75 M, and 150 M allogeneic MPCs in subjects with heart failure.
Read more! Heart Failure: Breathe More Easily2/6/2009 12:00:00 AM (MST)
Heart failure makes it hard for oxygen to get into the blood, causing shortness of breath.
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Heart Failure: Breathe More Easily
One of the earliest symptoms of heart failure is shortness of breath. Your heart can't function well enough to pump the blood out of your heart, and this causes blood to back up in the lung blood vessels. Fluid then leaks from your blood vessels into the air sacs in your lungs. This makes it hard for oxygen to get into the blood, causing shortness of breath.
You may experience breathlessness during exertion, such as when climbing a flight of stairs, or at rest--even at night when sleeping.
You can do several things to help yourself breathe more easily:
Eat a healthy diet and avoid sodium (salt). Keeping your sodium intake at a minimum is more than just not adding salt to food. Many prepared and fast foods already have high amounts of sodium added, so it is important to read the nutritional information on packaging. This will reduce the amount of fluid your body retains. Talk with your doctor about how to limit your sodium intake and what is best for you.
Pay attention to what your body is telling you. If you become fatigued during an activity, stop and rest. You can always postpone finishing a task that wears you out.
Sleep with several pillows propped behind your head and shoulders to make it easier to breathe at night. If you notice that you need to use many pillows, or more pillows than usual, to help you breathe comfortably, call your doctor right away.
Talk with your doctor about what level of activity is appropriate for you. Your doctor can help you gauge what you can and can't do.
Work with your doctor to develop an aerobic exercise program, then exercise every day. This will strengthen both your heart and lungs and help reduce the amount of fluid that seeps into your lungs.
Shortness of breath can be a serious problem. If you notice a sudden worsening or you feel breathless while at rest when you never have before, call your doctor immediately.
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Double-Blind, Placebo-Controlled, Multicenter Acute Study of Clinical Effectiveness of Nesiritide in Subjects With Decompensated Heart Failure (ASCEND HF)
The purpose of this study is to find out if Nesiritide (a human B-type natriuretic peptide/hBNP) as compared to placebo, plus the usual treatment for acute decompensated heart failure, helps to improve breathing difficulties, reduce readmissions to hospitals, and helps patients live longer.
Read more! CHF and Physical Activity2/6/2009 12:00:00 AM (MST)
If you have congestive heart failure, you may wonder if physical activity is good for you.
Hide Article CHF and Physical Activity2/6/2009 12:00:00 AM (MST)
Heart Failure and Physical Activity
If you have heart failure (HF), you may wonder if physical activity is good for you. How could putting more strain on your heart and making it work harder be a good thing? The truth is, moderate physical activity helps the heart get stronger.
Regular and moderate physical activity, such as walking, swimming or biking, can improve HF symptoms, reduce stress and increase energy levels. It can also decrease blood pressure, improve circulation and help you lose weight -- important factors in staying healthy, especially when you have heart failure.
Being physically active with this condition can be a struggle, and you may have to follow certain precautions. Talk with your doctor before starting a physical activity program. If you?re not used to physical activity and are nervous about starting, your doctor can help you develop a physical activity plan that fits your needs.
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Chronic Heart Failure Study
We are seeking individuals in the advanced stages of heart failure to participate in a research study at Mercy Gilbert Medical Center.
We are seeking individuals with significant narrowing or blockage in an artery in the heart to participate in a research study at Mercy Gilbert Medical Center.
